Dizriel Moon, smuggler, thief and occasional gun for hire, lives life her way and damn anyone who tries to tell her different. Stryker Donovan, a former Australian commando, seeks a quiet life in a small outback town after years of active service in distant war torn countries. When these two worlds collide the heat threatens to scorch them both.
After Dizriel saves Stryker from an intergalactic killer, he joins her and the mismatched crew of the Tequila Moon to revenge the murderer of his friends. As they race to get medicines to a small disease ravaged colony on a distant planet they must stay one step ahead of a galactic mob boss, who has a price on her head, and a merciless bounty hunter out for his blood.